Investment

This week’s family investment deals

Thiel Capital, the investment office of Peter Thiel, has invested in biotech group, EnClear Therapies. Thiel Capital seeded the US group with three other investors with $4 million.

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Investment

Family and principal investment groups participated in venture director deals totalling $68.1 billion in 2025, with life science investments accounting for $12.5 billion, according to FamCap Analytics. 
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The number of family/principal investment office deals might be down from last year, but the size of deals is picking up as family offices move into rounds, sometimes supporting $1 billion-plus. 
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Family offices and principal investment groups with the wherewithal are increasingly writing bigger cheques to participate in mega-deals, squeezing out sub-billion-dollar family offices from direct deals. 

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